0 White, S. N. Halbert, Natalie D. Taylor, K. H. Derr, James N. Womack, J. E. 2005 Animal Genetics 36 511-542 2005 bison, genetics, immunity, Brucella, Mycobacteria, Pasteurella, pathogens, Salmonella, TLR4, tuberculosis, wildlife health, Mycobacterium bovis, brucella abortus, bacteria Toll-like receptor 4 (TLR4) is a cell-surface receptor that activates innate and adaptive immune responses. Because it recognizes a broad class of pathogen associated molecular patterns, including lipopolysaccharides, TLR4 is a candidate gene for resistance to a large number of pathogens. Important examples are Gramnegative Salmonella,1 Pasteurella,2, and Brucella, as well as Mycobacteria,3 which include the causative agents of tuberculosis and Johne’s disease. Found in Bison Library, pdf on computerNatureBib ID: 652406