0 Aguirre, A. Alonso Starkey, Edward E. 1994 Conservation Biology 8 654-661 September 1994 154 disease, national parks, history, brucellosis, Yellowstone National Park, animal studies, bovine brucellosis, disease, lung-worm pneumonia, ungulates, wildlife health, general wildlife health studies Diseases of wildlife have significant management implications in a number of lands of the U.S. National Park Service due to increasing interactions between wildlife and domestic animals. We review the paleontology, history, and coevolution of infectious diseases in North American ungulates. We provide two examples related to bovine brucellosis in bison in Yellowstone National Park and lungworm pneumonia complex in bighorn sheep in several western national parks. These examples illustrate the difficulty of managing wild populations and their diseases in national parks and other protected areas. In some instances, human intervention may be justifiable in order to protect native populations, domestic animals, and humans from acquiring a disease. Found online, pdf on computer, citation in NatureBibNatureBib ID: 138122